Ergotamine is a medication primarily used to treat acute migraine attacks. It works by constricting blood vessels in the brain, which helps alleviate headache symptoms. This drug is often found in combination with caffeine to enhance its effectiveness. Ergotamine is derived from the ergot fungus, which has been used historically for various medicinal purposes. While effective for migraines, it can cause side effects such as nausea and dizziness. Due to its potential for serious complications, it is important for patients to use it under medical supervision.