East 22nd Street is a street located in various cities across the United States, often characterized by residential and commercial areas. In urban settings, it may feature a mix of homes, shops, and local businesses, contributing to the neighborhood's community feel. In cities like New York and Los Angeles, East 22nd Street can be found in diverse neighborhoods, reflecting the local culture and demographics. The street may also serve as a connector between major roads and public transportation, making it accessible for residents and visitors alike.