The Dukes of Newcastle is a title in the British peerage, created in 1665. The title has been held by the Cavendish family, who played significant roles in English politics and society. The first Duke, Thomas Pelham-Holles, was a prominent statesman and served as Prime Minister in the 18th century. The dukedom is associated with the Newcastle area, particularly Newcastle upon Tyne. The family has a rich history, including connections to the House of Lords and various estates, such as Clumber Park. The title has passed through several generations, maintaining its influence in British history.