Duke John II of Cleves (1458–1521) was a nobleman from the House of Cleves, a significant dynasty in the region of North Rhine-Westphalia, Germany. He ruled as Duke from 1511 until his death and was known for his efforts to strengthen his duchy through strategic marriages and alliances. John II was the son of Adolph I, Duke of Cleves, and he played a role in the political landscape of Renaissance Europe. His reign was marked by attempts to navigate the complex relationships between powerful neighbors, including France and the Holy Roman Empire.