Duke Charles III of Lorraine (1543–1608) was a significant noble figure in the Holy Roman Empire. He ruled the Duchy of Lorraine from 1545 until his death, playing a crucial role in the political landscape of the region. His reign was marked by efforts to strengthen the duchy and maintain its independence amid the conflicts of the time. Charles III was also known for his military involvement, particularly during the French Wars of Religion. He was a member of the House of Lorraine, a prominent family that influenced European politics. His legacy includes the promotion of arts and culture in Lorraine, contributing to its historical significance.