Doniphan is a city located in Missouri, United States. It is situated in Ripley County and is part of the Poplar Bluff micropolitan area. The city was founded in the mid-19th century and has a small population, reflecting its rural character. The city is named after Alexander Doniphan, a notable figure in the Mexican-American War and a prominent lawyer and politician. Doniphan is known for its close-knit community and offers various local amenities, including parks and small businesses, contributing to its charm as a small-town destination.