A "Dominant Negative" refers to a type of genetic mutation where a mutated gene product interferes with the function of the normal gene product. This can occur when the mutated protein competes with the normal protein, leading to a reduced overall function. Such mutations can have significant effects on biological processes and may contribute to various diseases. In the context of genetics, dominant negative mutations are often observed in tumor suppressor genes and oncogenes. These mutations can disrupt normal cellular functions, potentially leading to uncontrolled cell growth and cancer. Understanding dominant negative effects is crucial for developing targeted therapies in molecular medicine.