Direct Sequence is a method used in digital communication to spread a signal over a wider bandwidth. This technique involves multiplying the original data signal by a high-frequency carrier signal, resulting in a sequence of bits that can be transmitted more efficiently. It helps reduce interference and improves the signal's resistance to noise. In the context of spread spectrum technology, Direct Sequence is often used in systems like Wi-Fi and GPS. By spreading the signal, it allows multiple users to share the same frequency band without significant interference, enhancing overall communication reliability and performance.