Diffuse Large B-Cell Lymphoma (DLBCL) is a type of cancer that originates in the B-cells, which are a part of the immune system. It is characterized by the rapid growth of large abnormal cells in the lymphatic system, often leading to swollen lymph nodes, fever, weight loss, and night sweats. DLBCL is the most common form of non-Hodgkin lymphoma. Diagnosis typically involves a biopsy of the affected tissue, and treatment often includes chemotherapy, radiation therapy, or targeted therapies. The prognosis varies based on factors such as the patient's age, overall health, and how well the cancer responds to treatment.