To deplete means to reduce something to a very low level or to exhaust its supply. This can happen to natural resources, such as water, oil, or minerals, when they are used faster than they can be replenished. For example, overfishing can deplete fish populations, making it difficult for them to recover. In everyday life, people can also experience depletion. For instance, when someone works long hours without rest, they may feel mentally or physically exhausted. This type of depletion can affect productivity and overall well-being, highlighting the importance of balance and self-care.