The Della Rovere family was an influential Italian noble family during the Renaissance, particularly known for their role in the Roman Catholic Church. They produced several popes, including Pope Sixtus IV and Pope Julius II, who were significant figures in the history of the Church and the arts. The family's power and wealth were largely derived from their extensive landholdings and political alliances. They were patrons of the arts, commissioning works from renowned artists like Michelangelo and Raphael, which contributed to the cultural flourishing of the period.