Hernando de Soto was a Spanish explorer and conquistador born in 1496. He is best known for leading the first European expedition deep into the territory of the modern-day United States, specifically in the southeastern region. His journey, which began in 1539, aimed to find gold and other riches, and he is credited with the first European contact with several Native American tribes. De Soto's expedition traveled through areas that are now part of Florida, Georgia, Alabama, Mississippi, and Arkansas. Despite his search for wealth, he faced numerous challenges, including conflicts with indigenous peoples and harsh conditions. De Soto died in 1542, and his expedition ultimately failed to find the riches he sought.