DAMPs, or Damage-Associated Molecular Patterns, are molecules released by stressed or damaged cells. They play a crucial role in the body's immune response by signaling to the immune system that there is tissue injury or infection. DAMPs can activate various immune cells, helping to initiate healing processes and inflammation. These molecules can include proteins, nucleic acids, and other cellular components. When released, DAMPs interact with receptors on immune cells, such as pattern recognition receptors (PRRs), to trigger responses that help protect the body. Understanding DAMPs is important for research in areas like autoimmune diseases and inflammation.