Cystic Fibrosis Transmembrane Conductance Regulator
The Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) is a protein that functions as a channel for chloride ions across cell membranes. It plays a crucial role in maintaining the balance of salt and water in various tissues, particularly in the lungs and digestive system. Mutations in the CFTR gene can lead to the disease known as Cystic Fibrosis, which affects respiratory and digestive functions.
CFTR is essential for the production of thin, free-flowing mucus that protects the lungs and digestive tract. When CFTR is defective, mucus becomes thick and sticky, leading to blockages and infections in the lungs. This condition can also cause digestive issues, as the pancreas struggles to release enzymes needed for proper digestion.