"Cuckoo's Nest" refers to the novel "One Flew Over the Cuckoo's Nest" written by Ken Kesey in 1962. The story is set in a mental institution and follows the experiences of Randle McMurphy, a man who feigns insanity to escape a prison sentence. He challenges the oppressive authority of Nurse Ratched, the head nurse, and inspires other patients to reclaim their individuality. The novel explores themes of freedom, conformity, and the struggle against oppressive systems. It highlights the impact of mental health treatment during the 1960s and critiques the dehumanizing aspects of institutional care. The book was later adapted into a successful film in 1975, starring Jack Nicholson.