Crossed Aldol Reaction
The Crossed Aldol Reaction is a chemical reaction that involves the formation of a β-hydroxy carbonyl compound through the reaction of two different aldehydes or ketones. In this process, one carbonyl compound acts as a nucleophile, while the other serves as an electrophile. This reaction is particularly useful in organic synthesis for creating complex molecules.
In a typical Aldol Reaction, the nucleophile undergoes deprotonation to form an enolate ion, which then attacks the carbonyl carbon of the electrophile. After the initial aldol addition, dehydration can occur, leading to the formation of an α,β-unsaturated carbonyl compound. This reaction is valuable for building carbon-carbon bonds in organic chemistry.