Countess Caroline of Nassau-Usingen was born on January 1, 1746, in Nassau-Usingen, a small principality in present-day Germany. She was the daughter of Count Wilhelm of Nassau-Usingen and Countess Caroline of Nassau-Saarbrücken. Caroline became known for her role in the cultural and social life of her time, particularly in the context of the German Enlightenment. In 1764, she married Prince Friedrich Wilhelm of Hesse-Kassel, further strengthening the ties between noble families in Europe. Throughout her life, Countess Caroline was involved in various charitable activities and supported the arts, contributing to the cultural development of her region until her death in 1822.