Cori Disease, also known as Cori's disease or glycogen storage disease type III, is a rare genetic disorder that affects the body's ability to break down glycogen, a stored form of sugar. This condition is caused by a deficiency of the enzyme debranching enzyme, which is essential for the proper metabolism of glycogen. As a result, glycogen accumulates in the liver and muscles, leading to various health issues. Symptoms of Cori Disease can include low blood sugar, muscle weakness, and an enlarged liver. The severity of the disease can vary among individuals, and some may experience milder symptoms while others face more significant challenges. Early diagnosis and management are crucial for improving quality of life and preventing complications.