Connexin 34 is a protein that forms gap junctions, which are channels that allow communication between adjacent cells. It is part of the connexin family, which consists of various proteins that facilitate the transfer of ions and small molecules, playing a crucial role in cellular signaling and maintaining tissue homeostasis. This protein is primarily expressed in the nervous system and heart, where it helps coordinate cellular activities. Mutations or dysfunctions in Connexin 34 can lead to various health issues, including cardiac arrhythmias and neurological disorders, highlighting its importance in maintaining proper physiological functions.