Clarendon County is located in the central part of South Carolina, bordered by the Santee River to the north and the Pee Dee River to the east. It was established in 1785 and is known for its rich history and natural beauty, including lakes and wetlands. The county seat is Manning, which serves as a hub for local government and commerce. The area is primarily rural, with agriculture playing a significant role in the local economy. Clarendon County is also home to several parks and recreational areas, making it a destination for outdoor activities such as fishing and hiking.