Chromosomal deletion syndromes occur when a portion of a chromosome is missing or deleted. This loss of genetic material can lead to various developmental and health issues, depending on which genes are affected. Common examples include Williams syndrome and Cri du Chat syndrome, each associated with specific physical and cognitive characteristics. The severity of symptoms in chromosomal deletion syndromes can vary widely among individuals. Some may experience mild developmental delays, while others may face more significant challenges, such as heart defects or learning disabilities. Early diagnosis and intervention can help manage symptoms and improve quality of life for those affected.