Chromatin Immunoprecipitation Sequencing (ChIP-seq) is a powerful technique used to study the interactions between proteins and DNA within cells. It involves cross-linking proteins to DNA, then using specific antibodies to isolate the protein-DNA complexes. After purification, the DNA is sequenced to identify the regions of the genome that are bound by the protein of interest. This method helps researchers understand gene regulation and the role of transcription factors in controlling gene expression. By analyzing the sequencing data, scientists can map binding sites across the genome, providing insights into cellular processes and potential implications for diseases like cancer.