ChIP-seq (Chromatin Immunoprecipitation followed by sequencing) is a powerful technique used to study protein-DNA interactions in cells. It allows researchers to identify the binding sites of specific proteins, such as transcription factors, on the genome. By using antibodies that target these proteins, scientists can isolate the DNA they are bound to and then sequence it to determine its location. This method provides insights into gene regulation and the mechanisms of epigenetics. By analyzing the data, researchers can understand how proteins influence gene expression and how changes in these interactions may lead to diseases, including cancer.