Cape Girardeau County is located in the southeastern part of Missouri, bordered by the Mississippi River to the east. The county seat is the city of Cape Girardeau, which is known for its rich history and vibrant community. The area features a mix of urban and rural landscapes, with various parks and recreational opportunities available for residents and visitors. The county was established in 1812 and has a diverse population. It is home to several educational institutions, including Southeast Missouri State University. The local economy is supported by agriculture, manufacturing, and healthcare, contributing to the overall growth and development of the region.