The Cancer Prevention Study-3 (CPS-3) is a long-term research project initiated by the American Cancer Society to better understand the causes of cancer and improve prevention strategies. Launched in 2006, it aims to enroll over 300,000 participants across the United States, collecting data on lifestyle, environmental factors, and genetic information. Participants in CPS-3 provide information through surveys and blood samples, which help researchers identify risk factors associated with various types of cancer. The study's findings are expected to contribute significantly to cancer prevention efforts and enhance public health initiatives in the future.