CYP2E1 is an enzyme that belongs to the cytochrome P450 family, which plays a crucial role in the metabolism of various substances in the body. It is primarily found in the liver and is involved in the breakdown of drugs, alcohol, and other chemicals. This enzyme helps convert these substances into forms that can be easily eliminated from the body. In addition to its role in drug metabolism, CYP2E1 is also important in the activation of certain procarcinogens, which can lead to cancer. Factors such as alcohol consumption and obesity can influence the activity of CYP2E1, potentially affecting how the body processes different compounds and responds to medications.