A "CGG repeat" refers to a specific sequence of DNA where the nucleotides cytosine (C) and guanine (G) are repeated multiple times. This sequence is particularly significant in the context of certain genetic disorders, such as Fragile X syndrome, which is caused by an expansion of CGG repeats in the FMR1 gene. In healthy individuals, the number of CGG repeats is typically low, but when the repeats exceed a certain threshold, it can lead to gene silencing and associated health issues. Understanding CGG repeats is crucial for genetic testing and counseling, especially for families affected by related conditions.