C5 Complement is a protein that plays a crucial role in the immune system. It is part of the complement system, which helps the body fight infections and clear damaged cells. When activated, C5 is split into two fragments, C5a and C5b, each with distinct functions. C5a acts as a powerful inflammatory mediator, attracting immune cells to sites of infection or injury. In contrast, C5b initiates the formation of the membrane attack complex, which can directly destroy pathogens by creating pores in their membranes. Together, these actions enhance the body's ability to respond to threats.