Bufo Alvarius, also known as the Colorado River toad, is a large toad native to the southwestern United States and northern Mexico. This toad secretes a potent substance called 5-MeO-DMT from its parotoid glands, which can be harvested and dried for use. When vaporized and inhaled, this substance produces intense psychoactive effects, often described as profound and mystical experiences. The use of Bufo Alvarius for its psychoactive properties has gained popularity in recent years, particularly in spiritual and therapeutic contexts. However, it is important to note that the toad's secretion can be toxic if ingested improperly, and its collection raises ethical concerns regarding wildlife conservation.