Blood coagulation factors are proteins in the blood that play a crucial role in the process of blood clotting, also known as hemostasis. When a blood vessel is injured, these factors work together in a complex cascade to form a stable clot, preventing excessive bleeding. There are several key factors, each designated by a Roman numeral, such as Factor I (fibrinogen) and Factor VIII (antihemophilic factor). These factors are produced mainly in the liver and require certain vitamins, particularly Vitamin K, for their synthesis. Deficiencies or abnormalities in any of these factors can lead to bleeding disorders, such as hemophilia, where the blood does not clot properly, resulting in prolonged bleeding.