Blighttown is home to various creatures and beings, primarily the Toxic Rats and Blighttown's Undead. These inhabitants have adapted to the toxic environment, showcasing resilience despite the harsh conditions. The area is known for its dangerous terrain and poisonous atmosphere, which affects both the creatures and any adventurers who enter. Another notable group in Blighttown is the Basilisks, which are small, frog-like monsters that can inflict petrification. Additionally, the Queelag's Domain is nearby, where players encounter Quelaag, a half-woman, half-spider creature who guards the area. These inhabitants contribute to the eerie and perilous nature of Blighttown.