Biguanides are a class of medications primarily used to treat type 2 diabetes. The most well-known biguanide is metformin, which helps lower blood sugar levels by improving insulin sensitivity and reducing glucose production in the liver. These medications are often prescribed as part of a comprehensive diabetes management plan, which may include diet and exercise. Biguanides are generally considered safe and effective, but they can have side effects, such as gastrointestinal issues. Regular monitoring and consultation with a healthcare provider are essential for optimal use.