Beta-3 adrenergic receptors are a type of protein found in various tissues, primarily in adipose (fat) tissue and the bladder. They play a crucial role in regulating metabolism, particularly in the breakdown of fat and the generation of heat. When activated, these receptors can enhance lipolysis, which is the process of breaking down fat stores for energy. In addition to their role in fat metabolism, Beta-3 adrenergic receptors are also involved in bladder function. They help relax the bladder muscle, which can improve urinary control. This makes them a target for certain medications aimed at treating conditions like overactive bladder.