The Beta-1 receptor is a type of protein found on the surface of certain cells, primarily in the heart. It belongs to a larger family of receptors known as beta-adrenergic receptors, which respond to hormones like epinephrine and norepinephrine. When activated, the Beta-1 receptor increases heart rate and the force of heart contractions, playing a crucial role in the body's response to stress and physical activity. In addition to its effects on the heart, the Beta-1 receptor is also involved in regulating blood pressure and metabolism. Medications that target this receptor, known as beta-blockers, are commonly used to treat conditions such as hypertension and heart failure. By blocking the action of epinephrine, these drugs help to lower heart rate and reduce the workload on the heart.