B-cell neoplasms are a group of cancers that originate from B-cells, a type of white blood cell responsible for producing antibodies. These neoplasms can be classified into various types, including non-Hodgkin lymphoma, Hodgkin lymphoma, and chronic lymphocytic leukemia. They can affect the lymphatic system and other organs, leading to symptoms such as swollen lymph nodes, fever, and fatigue. Diagnosis typically involves blood tests, imaging studies, and a biopsy to examine the affected tissue. Treatment options may include chemotherapy, radiation therapy, and targeted therapies, depending on the specific type and stage of the neoplasm. Early detection is crucial for improving outcomes.