The B&O Warehouse is a historic building located in Baltimore, Maryland. Originally constructed in the 19th century, it served as a freight depot for the Baltimore and Ohio Railroad, one of the oldest railroads in the United States. The warehouse played a crucial role in the transportation of goods and materials during the industrial era. Today, the B&O Warehouse has been repurposed and is often used for events and exhibitions. It stands as a testament to the region's rich transportation history and is part of the larger B&O Railroad Museum, which showcases the evolution of rail travel and its impact on American society.