Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease that affects nerve cells in the brain and spinal cord. It leads to the gradual loss of muscle control, resulting in weakness, difficulty speaking, and eventually paralysis. The exact cause of ALS is not fully understood, but genetic and environmental factors may play a role. ALS is often referred to as Lou Gehrig's disease, named after the famous baseball player who was diagnosed with it. There is currently no cure for ALS, but treatments are available to help manage symptoms and improve quality of life for those affected.