Adrenomyeloneuropathy is a genetic disorder that primarily affects the nervous system and adrenal glands. It is part of a group of conditions known as X-linked adrenoleukodystrophy (X-ALD) and is caused by mutations in the ABCD1 gene. This condition leads to the accumulation of very long-chain fatty acids in the body, which can damage nerve cells and adrenal tissues. Symptoms of adrenomyeloneuropathy typically appear in adulthood and may include progressive weakness, sensory loss, and adrenal insufficiency. Diagnosis is often made through genetic testing and measurement of fatty acid levels in the blood. Treatment focuses on managing symptoms and may involve hormone replacement therapy for adrenal insufficiency.