Acute Intermittent Porphyria
Acute Intermittent Porphyria (AIP) is a rare genetic disorder that affects the production of heme, a component of hemoglobin in red blood cells. It is caused by a deficiency in the enzyme porphobilinogen deaminase, leading to the accumulation of porphyrins in the body. Symptoms can include severe abdominal pain, nausea, vomiting, and neurological issues, which can vary in intensity and duration.
AIP is often triggered by factors such as certain medications, hormonal changes, fasting, or stress. Diagnosis typically involves urine tests to detect elevated porphyrins. Treatment focuses on managing symptoms and avoiding triggers to prevent attacks.