ALDH, or aldehyde dehydrogenase, is an enzyme that plays a crucial role in the metabolism of aldehydes, which are reactive compounds found in various biological processes. It helps convert these aldehydes into less toxic substances, primarily by transforming them into carboxylic acids. This process is essential for detoxifying harmful substances in the body. There are several types of ALDH, each with specific functions and tissue distributions. For example, ALDH2 is particularly important in the liver and is involved in breaking down alcohol. Variations in ALDH genes can affect individual responses to alcohol and certain medications, influencing health outcomes.