AGPAT3 is a gene that encodes an enzyme involved in lipid metabolism, specifically in the synthesis of phospholipids. This enzyme plays a crucial role in converting certain fatty acids into lysophosphatidic acid, which is important for various cellular functions, including cell signaling and growth. Mutations in the AGPAT3 gene can lead to metabolic disorders, affecting how the body processes fats. Research has shown that AGPAT3 is linked to conditions such as lipodystrophy, where there is an abnormal distribution of body fat. Understanding AGPAT3 is essential for developing treatments for these metabolic issues.