A 384-well plate is a laboratory tool used for high-throughput screening in biological and chemical research. It consists of 384 small wells arranged in a grid, allowing scientists to conduct multiple experiments simultaneously. Each well can hold a small volume of liquid, making it efficient for testing various samples or conditions. These plates are commonly made from materials like polystyrene and are compatible with automated liquid handling systems. The design of the 384-well plate enables researchers to save time and resources while increasing the amount of data collected in a single experiment, which is essential for drug discovery and other applications.