The 1931 United States Senate Election was held to fill the vacancy left by the death of Senator Samuel D. Jackson of Indiana. The election took place on November 3, 1931, and was notable for the Democratic Party's strong performance during a time of economic hardship due to the Great Depression. Frederick Van Nuys, the Democratic candidate, won the election against Republican opponent John W. Boehne. Van Nuys's victory contributed to the Democratic majority in the Senate, reflecting the shifting political landscape of the early 1930s as voters sought change amid economic challenges.