The year 1501 marked the beginning of the 16th century and was significant in various historical contexts. It was during this time that the Renaissance was flourishing in Europe, leading to advancements in art, science, and exploration. Notably, Leonardo da Vinci was active, contributing to the rich cultural landscape of the period. In 1501, Portugal continued its maritime explorations, expanding trade routes and establishing colonies. This year also saw the birth of Michel de Nostredame, known as Nostradamus, who would later become famous for his prophecies. The events of 1501 set the stage for significant developments in the years to come.