Trisomy 18, also known as Edwards syndrome, is a genetic condition caused by the presence of an extra 18th chromosome. This abnormality leads to severe developmental delays and various physical abnormalities. Common features include a small head, clenched fists, and heart defects. Most affected infants face significant health challenges. The prognosis for Trisomy 18 is generally poor, with many infants not surviving past their first year of life. Those who do survive often require extensive medical care and support. Early diagnosis through prenatal screening can help families prepare for the challenges associated with this condition.