Tissue degeneration refers to the process where cells in a specific tissue lose their normal structure and function, often leading to a decline in the tissue's overall health. This can occur due to various factors, including aging, injury, or diseases such as diabetes and arthritis. As tissues degenerate, they may become weaker and less capable of performing their intended roles in the body. Common examples of tissue degeneration include muscle atrophy, where muscle fibers shrink and weaken, and cartilage degeneration, which can lead to joint pain and stiffness. Understanding tissue degeneration is important for developing treatments and interventions to restore or maintain tissue health.