Tetra-amelia syndrome is a rare genetic disorder characterized by the absence of all four limbs. This condition is caused by mutations in the WNT3 gene, which plays a crucial role in limb development during early pregnancy. Individuals with this syndrome may also have other physical abnormalities, such as facial deformities or issues with internal organs. The syndrome is extremely rare, with only a few documented cases worldwide. Diagnosis typically occurs through prenatal imaging or at birth. Treatment focuses on supportive care, including physical therapy and prosthetics, to help individuals achieve greater mobility and independence in their daily lives.