Secondary immune deficiency occurs when the immune system is weakened due to external factors, rather than being inherited. This condition can result from various causes, including infections like HIV, certain medications, malnutrition, or chronic diseases such as diabetes or cancer. As a result, the body becomes more susceptible to infections and illnesses. Unlike primary immune deficiency, which is present at birth, secondary immune deficiency can develop at any age. Treatment often focuses on addressing the underlying cause, such as managing diabetes or adjusting medications. In some cases, patients may require additional therapies to help boost their immune response.