Rifaximin is an antibiotic primarily used to treat gastrointestinal infections, particularly those caused by bacteria. It works by inhibiting bacterial RNA synthesis, effectively reducing the growth of harmful bacteria in the gut. Rifaximin is often prescribed for conditions like traveler's diarrhea and irritable bowel syndrome with diarrhea. This medication is unique because it is minimally absorbed into the bloodstream, allowing it to act directly in the intestines. As a result, it has a lower risk of systemic side effects compared to other antibiotics. Rifaximin is generally well-tolerated, making it a preferred option for treating certain gut-related issues.