Primary immunodeficiency disorders are a group of rare conditions where the immune system is not functioning properly from birth. This can make individuals more susceptible to infections, as their bodies struggle to fight off bacteria, viruses, and other pathogens. These disorders can be caused by genetic mutations that affect various components of the immune system. Symptoms of primary immunodeficiency can include frequent infections, delayed growth, and autoimmune issues. Diagnosis often involves blood tests and genetic testing to identify the specific disorder. Treatment may include immunoglobulin therapy, antibiotics, or other medications to help manage symptoms and improve immune function.